These censored values below the LoD influence the diagnostic performance of these assays compared to highly sensitive cTnI (hs-cTnI) assays. In the diagnosis of acute myocardial infarction (AMI) many patients present with troponin concentrations below the LoD of contemporary sensitive cardiac troponin I (cs-cTnI) assays. 10 Division of Cardiology, Department of Medicine III, Goethe University Frankfurt, Frankfurt, Germany DZHK (German Centre for Cardiovascular Research), partner site Rhein-Main, Germany limit of detection (LoD) is the minimal amount of a substance that can be consistently detected.10 Division of Cardiology, Department of Medicine III, Goethe University Frankfurt, Frankfurt, Germany DZHK (German Centre for Cardiovascular Research), partner site Rhein-Main, Germany 1 Institute for Cardiovascular Regeneration, Center of Molecular Medicine and DZHK (German Centre for Cardiovascular Research), partner site Rhein-Main, Germany.9 Institute for Clinical Chemistry and Laboratory Medicine, University Medical Center, Johannes Gutenberg University, Mainz, Germany.8 Division of Cardiology, Department of Medicine III, Goethe University Frankfurt, Frankfurt, Germany DZHK (German Centre for Cardiovascular Research), partner site Rhein-Main, Germany.7 Department of Medicine II, University Medical Center, Johannes Gutenberg University, Mainz, Germany DZHK (German Centre for Cardiovascular Research), partner site Rhein-Main, Germany.6 Heart Center, University of Cologne, Cologne, Germany.5 Department of Internal Medicine, Federal Armed Forces Hospital, Koblenz, Germany.4 Department of Medicine II, University Medical Center, Johannes Gutenberg University, Mainz, Germany 3rd Department of Cardiology, Aristotle University of Thessaloniki, Ippokrateio Hospital, Thessaloniki, Greece.3 Clinic for General and Interventional Cardiology, University Heart Centre Hamburg, Hamburg, Germany DZHK (German Centre for Cardiovascular Research), partner site Hamburg/Kiel/Lübeck, Germany.2 Division of Cardiology, Department of Medicine III, Goethe University Frankfurt, Frankfurt, Germany.
1 Institute for Cardiovascular Regeneration, Center of Molecular Medicine and DZHK (German Centre for Cardiovascular Research), partner site Rhein-Main, Germany.